BDBM50121176 3-(2'-oxo-1',2'-dihydrospiro[cyclopentane-1,3'-indol]-5'-yl)benzonitrile::CHEMBL117573

SMILES O=C1Nc2ccc(cc2C11CCCC1)-c1cccc(c1)C#N

InChI Key InChIKey=QOLHBLXTCPSWBK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50121176   

TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50121176(3-(2'-oxo-1',2'-dihydrospiro[cyclopentane-1,3'-ind...)
Affinity DataIC50:  21nMAssay Description:Progesterone receptor antagonist activity based on its ability to block progesterone induced alkaline phosphatase in the human breast cancer cell lin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed