BDBM50121417 CHEMBL119646::Lithium; 2-(2,4-dichloro-benzoylamino)-5-(2-methylsulfanyl-ethoxy)-benzoate

SMILES CSCCOc1ccc(NC(=O)c2ccc(Cl)cc2Cl)c(c1)C([O-])=O

InChI Key InChIKey=NUFOUZIOJRXDFK-UHFFFAOYSA-M

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50121417   

TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50121417(CHEMBL119646 | Lithium; 2-(2,4-dichloro-benzoylami...)
Affinity DataKi:  1.60E+3nMAssay Description:Ligand binding affinity was determined by displacement of a tritiated tracer by the unlabeled compound to a GST-PPAR fusion protein for Peroxisome pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50121417(CHEMBL119646 | Lithium; 2-(2,4-dichloro-benzoylami...)
Affinity DataKi:  1.90E+4nMAssay Description:Ligand binding affinity was determined by displacement of a tritiated tracer by the unlabeled compound to a GST-PPAR fusion protein for Peroxisome pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50121417(CHEMBL119646 | Lithium; 2-(2,4-dichloro-benzoylami...)
Affinity DataEC50:  600nMAssay Description:Transactivation potency was measured by luciferase activity in Caco- 2/TC7 cells transiently co-transfected for the fusion-protein Gal4-PPAR gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50121417(CHEMBL119646 | Lithium; 2-(2,4-dichloro-benzoylami...)
Affinity DataEC50:  2.50E+3nMAssay Description:Ligand binding affinity was determined by displacement of a tritiated tracer by the unlabeled compound to a GST-PPAR fusion protein for Peroxisome pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed