BDBM50121587 CHEMBL153395::cis-4-(2-{4-[Methyl-(2-phenyl-cyclopropylmethyl)-amino]-6-piperazin-1-yl-[1,3,5]triazin-2-ylamino}-ethyl)-phenol
SMILES CN(C[C@@H]1C[C@@H]1c1ccccc1)c1nc(NCCc2ccc(O)cc2)nc(n1)N1CCNCC1
InChI Key InChIKey=SNKMXSCMYMYPLC-JTHBVZDNSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50121587
Affinity DataKi: 40nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.24E+3nMAssay Description:In vitro binding affinity towards human Estrogen receptor alpha using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
Affinity DataEC50: 500nMAssay Description:Agonist effect on transcriptional activation in T47D cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of 1 nM 17-beta-estradiol induced transcriptional activation in T47D cells expressing estrogen receptor betaMore data for this Ligand-Target Pair
Affinity DataIC50: 565nMAssay Description:In vitro inhibition of transcriptional activation induced by 1 nM 17-beta estradiol in T47D cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair