BDBM50124566 (R)-2-((R)-(2-ethoxyphenoxy)(phenyl)methyl)morpholine::(S)-2-((S)-(2-ethoxyphenoxy)(phenyl)methyl)morpholine::2-((2-ethoxyphenoxy)(phenyl)methyl)morpholine::2-[(2-Ethoxy-phenoxy)-phenyl-methyl]-morpholine::2-[2-ethoxyphenoxy(phenyl)methyl]-1,4-oxazinane::CHEMBL14370::REBOXETINE::rac-syn-2-((2-ethoxyphenoxy)(phenyl)methyl)morpholine

SMILES CCOc1ccccc1OC(C1CNCCO1)c1ccccc1

InChI Key InChIKey=CBQGYUDMJHNJBX-UHFFFAOYSA-N

Data  14 KI  19 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50124566   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50124566((R)-2-((R)-(2-ethoxyphenoxy)(phenyl)methyl)morphol...)
Affinity DataIC50:  242nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50124566((R)-2-((R)-(2-ethoxyphenoxy)(phenyl)methyl)morphol...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed