BDBM50124608 (5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysen-9-yl)-methanol::CHEMBL8637

SMILES COc1c(CO)ccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12

InChI Key InChIKey=BQDLKNZJOSLJEM-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50124608   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50124608((5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H...)
Affinity DataKi:  6.60nMAssay Description:Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50124608((5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H...)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]-progesterone from human Progesterone receptor AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50124608((5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H...)
Affinity DataEC50:  53nMAssay Description:Binding affinity towards aldosterone receptor (Mineralocorticoid receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed