BDBM50124769 CHEMBL3622939

SMILES Cc1cn(cc1CN1CC[C@@H](O)C1)-c1ccnc(Nc2cc(C)c(OCCO)c(C)c2)n1

InChI Key InChIKey=UQRBPKDDLLIVLG-OAQYLSRUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50124769   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124769(CHEMBL3622939)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124769(CHEMBL3622939)
Affinity DataIC50:  17nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed