BDBM50126147 CHEMBL3629571

SMILES OC(=O)C1CC1C(=O)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=ZBRKMOHDGFGXLN-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50126147   

TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Colorado College

Curated by ChEMBL
LigandPNGBDBM50126147(CHEMBL3629571)
Affinity DataIC50:  20nMAssay Description:Inhibition of human KMOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Colorado College

Curated by ChEMBL
LigandPNGBDBM50126147(CHEMBL3629571)
Affinity DataIC50:  40nMAssay Description:Inhibition of KMO (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Tes Pharma

Curated by ChEMBL
LigandPNGBDBM50126147(CHEMBL3629571)
Affinity DataIC50:  20nMAssay Description:Inhibition of rat liver KMO using [3,5-3H]-kynurenine substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Saccharomyces cerevisiae (strain ATCC 204508 / S28...)
Colorado College

Curated by ChEMBL
LigandPNGBDBM50126147(CHEMBL3629571)
Affinity DataIC50:  74nMAssay Description:Inhibition of yeast KMOMore data for this Ligand-Target Pair