BDBM50127144 6-(3-methylphenyl)pteridine-2,4,7-triamine (17)::6-m-Tolyl-pteridine-2,4,7-triamine::CHEMBL48189

SMILES Cc1cccc(c1)-c1nc2c(N)nc(N)nc2nc1N

InChI Key InChIKey=YCKFHKBIDNIARX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50127144   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50127144(6-(3-methylphenyl)pteridine-2,4,7-triamine (17) | ...)
Affinity DataIC50:  18nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase(DHFR) of Toxoplasma gondiiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Max Planck Institute of Molecular Physiology

LigandPNGBDBM50127144(6-(3-methylphenyl)pteridine-2,4,7-triamine (17) | ...)
Affinity DataIC50:  2.02E+4nMpH: 7.5Assay Description:A stock solution of 5 % DMSO (BioReagent for molecular biology, Sigma Aldrich) in water was prepared. The CK1 substrate peptide RRKDLHDDEEDEAMSITA (J...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed