BDBM50128581 Biphenyl-3-yl-carbamic acid cyclohexyl ester::CHEMBL77767::URB602::biphenyl-3-ylcarbamic acid cyclohexyl ester::cyclohexyl biphenyl-3-ylcarbamate
SMILES O=C(Nc1cccc(c1)-c1ccccc1)OC1CCCCC1
InChI Key InChIKey=HHVUFQYJOSFTEH-UHFFFAOYSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50128581
Affinity DataIC50: 2.23E+5nMpH: 8.0Assay Description:The measurement of the ability of URB602 compound to inhibit MGL activity. More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Fatty acid amide hydrolase inhibitory activity in rat brain membrane using [3H]-anandamide as a substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MGLMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Louvain Drug Research Institute
Curated by ChEMBL
Louvain Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 5.65E+3nMAssay Description:Inhibition of human FAAHMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of MAGL in Wistar rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of MAGL (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MGL activity using [3H]2-oleoylglycerol substrate by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of MAGL from Wistar rat brain using 2-monooleoyl[1,2,3-H]glycerol as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of Wistar rat MAGL using 2-monooleoyl[1,2,3-3H]glycerol as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of recombinant human MAGL using 7-HRA as substrate preincubated for 60 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.98E+4nMAssay Description:Inhibition of MAGL in mouse B16-F10 cells using 7-HRA as substrate preincubated for 60 mins followed by substrate addition measured every 2.5 mins fo...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Louvain Drug Research Institute
Curated by ChEMBL
Louvain Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 5.75E+3nMAssay Description:Inhibition of human recombinant FAAH-maltose binding proteinMore data for this Ligand-Target Pair