BDBM50129527 5-(2',4'-Dichloro-biphenyl-4-yl)-1-pyridin-3-yl-1H-pyrazole-3-carboxylic acid (1H-tetrazol-5-ylmethyl)-amide::CHEMBL307342

SMILES Clc1ccc(c(Cl)c1)-c1ccc(cc1)-c1cc(nn1-c1cccnc1)C(=O)NCc1nnn[nH]1

InChI Key InChIKey=JPMLNAZNRRYWQE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50129527   

TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50129527(5-(2',4'-Dichloro-biphenyl-4-yl)-1-pyridin-3-yl-1H...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibitory activity against Enterococci faecalis methionyl-tRNA synthetase (EfMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50129527(5-(2',4'-Dichloro-biphenyl-4-yl)-1-pyridin-3-yl-1H...)
Affinity DataIC50:  130nMAssay Description:Inhibitory activity against human methionyl-tRNA synthetase (hMetRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50129527(5-(2',4'-Dichloro-biphenyl-4-yl)-1-pyridin-3-yl-1H...)
Affinity DataIC50:  1.38E+4nMAssay Description:Inhibitory activity against Enterococci faecalis methionyl-tRNA synthetase (EfMetRS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed