BDBM50130285 6-Bromo-1-(4-methoxy-3-piperazin-1-yl-benzenesulfonyl)-1H-indole::CHEMBL96745

SMILES COc1ccc(cc1N1CCNCC1)S(=O)(=O)n1ccc2ccc(Br)cc12

InChI Key InChIKey=IAXDNLOYHAJESK-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50130285   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Hec Pharm Group

Curated by ChEMBL
LigandPNGBDBM50130285(6-Bromo-1-(4-methoxy-3-piperazin-1-yl-benzenesulfo...)
Affinity DataKi:  0.260nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in CHO cell membranes incubated for 120 mins by scintillation counter methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Hec Pharm Group

Curated by ChEMBL
LigandPNGBDBM50130285(6-Bromo-1-(4-methoxy-3-piperazin-1-yl-benzenesulfo...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Hec Pharm Group

Curated by ChEMBL
LigandPNGBDBM50130285(6-Bromo-1-(4-methoxy-3-piperazin-1-yl-benzenesulfo...)
Affinity DataIC50:  3.60nMAssay Description:Antagonist activity at recombinant human 5HT6R expressed in CHO cells assessed as inhibition of 5HT-stimulated cAMP accumulation incubated for 4 hrs ...More data for this Ligand-Target Pair
In DepthDetails PubMed