BDBM50131806 CHEMBL3634339
SMILES COc1cnc(cn1)C(=O)Nc1cc(ccn1)[C@@]1(C)N=C(N)CO[C@@H]1F
InChI Key InChIKey=MFDHEHSRVZGAHP-JKSUJKDBSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50131806
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of BACE1 in human SKNBE2 cells expressing wild type human APP695 assessed as reduction in amyloid beta-42 production after 18 hrs by sandw...More data for this Ligand-Target Pair
Affinity DataIC50: 3.47E+3nMAssay Description:Inhibition of BACE1 (unknown origin) using APP Swedish mutant harboring Lys-Met/Asn-Leu mutation in beta-secretase cleavage site as substrate by FRET...More data for this Ligand-Target Pair