BDBM50132355 2-(4-Chloro-phenyl)-6-morpholin-4-yl-pyran-4-one::2-(4-chlorophenyl)-6-morpholino-4H-pyran-4-one::CHEMBL105612

SMILES Clc1ccc(cc1)-c1cc(=O)cc(o1)N1CCOCC1

InChI Key InChIKey=VYDDKZSYMMZLQU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50132355   

TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50132355(2-(4-Chloro-phenyl)-6-morpholin-4-yl-pyran-4-one |...)
Affinity DataIC50:  180nMAssay Description:In vitro inhibition of DNA-dependent protein kinase(DNA-PK) from HeLa (human carcinoma) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50132355(2-(4-Chloro-phenyl)-6-morpholin-4-yl-pyran-4-one |...)
Affinity DataIC50:  180nMAssay Description:Inhibition of DNA-PK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50132355(2-(4-Chloro-phenyl)-6-morpholin-4-yl-pyran-4-one |...)
Affinity DataIC50:  180nMAssay Description:Inhibition of DNA-PK in HeLa cell nuclear extractsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed