BDBM50132357 (E)-3-[3'-(6-Morpholin-4-yl-4-oxo-4H-thiopyran-2-yl)-biphenyl-2-yl]-acrylic acid methyl ester::3-[3'-(6-morpholin-4-yl-4-oxo-4H-thiopyran-2-yl)-biphenyl-2-yl]-acrylic acid methyl ester::CHEMBL431228

SMILES COC(=O)\C=C\c1ccccc1-c1cccc(c1)-c1cc(=O)cc(s1)N1CCOCC1

InChI Key InChIKey=UWOZLXCSAGSXNK-MDZDMXLPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50132357   

TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50132357((E)-3-[3'-(6-Morpholin-4-yl-4-oxo-4H-thiopyran-2-y...)
Affinity DataIC50:  840nMAssay Description:Inhibition of DNA-PK in HeLa cell nuclear extractsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50132357((E)-3-[3'-(6-Morpholin-4-yl-4-oxo-4H-thiopyran-2-y...)
Affinity DataIC50:  840nMAssay Description:In vitro inhibition of DNA-dependent protein kinase(DNA-PK) from HeLa (human carcinoma) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed