BDBM50132365 2-(4-Methoxy-phenyl)-6-morpholin-4-yl-thiopyran-4-one::6-(4-methoxyphenyl)-2-morpholin-4-yl-4H-thiopyran-4-one::CHEMBL321784

SMILES COc1ccc(cc1)-c1cc(=O)cc(s1)N1CCOCC1

InChI Key InChIKey=XQTRMYUJFYVIMG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50132365   

TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50132365(2-(4-Methoxy-phenyl)-6-morpholin-4-yl-thiopyran-4-...)
Affinity DataIC50:  280nMAssay Description:In vitro inhibition of DNA-dependent protein kinase(DNA-PK) from HeLa (human carcinoma) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50132365(2-(4-Methoxy-phenyl)-6-morpholin-4-yl-thiopyran-4-...)
Affinity DataIC50:  280nMAssay Description:Inhibition of DNA-PK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50132365(2-(4-Methoxy-phenyl)-6-morpholin-4-yl-thiopyran-4-...)
Affinity DataIC50:  280nMAssay Description:Inhibition of DNA-PK in HeLa cell nuclear extractsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50132365(2-(4-Methoxy-phenyl)-6-morpholin-4-yl-thiopyran-4-...)
Affinity DataIC50:  280nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed