BDBM50132743 1-(2,6-Difluoro-benzyl)-5-(3-methoxy-phenyl)-6-methyl-3-{2-[(pyridin-2-ylmethyl)-amino]-ethyl}-1H-pyrimidine-2,4-dione::CHEMBL325942

SMILES COc1cccc(c1)-c1c(C)n(Cc2c(F)cccc2F)c(=O)n(CCNCc2ccccn2)c1=O

InChI Key InChIKey=VOLXEUOMDAYBKB-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50132743   

TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132743(1-(2,6-Difluoro-benzyl)-5-(3-methoxy-phenyl)-6-met...)
Affinity DataKi:  550nMAssay Description:Ability to inhibit des-Gly10[125I-Tyr5,DLeu6,NMeLeu7, Pro9-NEt]-GnRH radioligand binding to the cloned human gonadotropin-releasing hormone receptor ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed