BDBM50133016 (7-Chloro-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone::(7-chloro-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone::CHEMBL338051

SMILES CN1CCN(CC1)C(=O)c1cc2cccc(Cl)c2[nH]1

InChI Key InChIKey=DJLVUHAOULMUID-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50133016   

TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50133016((7-Chloro-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]histamine from recombinant human histamine H4 receptor in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50133016((7-Chloro-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]- histamine from the recombinant human histamine H4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50133016((7-Chloro-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  19.9nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50133016((7-Chloro-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  1.90E+7nMAssay Description:Antagonist activity at Homo sapiens (human) histamine H4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50133016((7-Chloro-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  1.90E+7nMAssay Description:Antagonist activity at Homo sapiens (human) histamine H4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article