BDBM50133778 2,4(5)-Diphenylimidazole::2,4-diphenyl-1H-imidazole::2,5-Diphenyl-1H-imidazole::CHEMBL327027

SMILES c1[nH]c(nc1-c1ccccc1)-c1ccccc1

InChI Key InChIKey=FHHCKYIBYRNHOZ-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50133778   

TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50133778(2,4(5)-Diphenylimidazole | 2,4-diphenyl-1H-imidazo...)
Affinity DataKi:  34nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radiogigand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50133778(2,4(5)-Diphenylimidazole | 2,4-diphenyl-1H-imidazo...)
Affinity DataIC50:  4.06E+4nMAssay Description:Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 8 subunit alpha(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50133778(2,4(5)-Diphenylimidazole | 2,4-diphenyl-1H-imidazo...)
Affinity DataIC50:  3.22E+4nMAssay Description:Inhibition of rat NaV1.6-mediated current expressed in human HEK293 cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50133778(2,4(5)-Diphenylimidazole | 2,4-diphenyl-1H-imidazo...)
Affinity DataIC50:  4.06E+4nMAssay Description:Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed