BDBM50134392 CHEMBL3747423

SMILES CCc1cnn2c(Nc3cccc(OC)c3)c(cnc12)C(N)=O

InChI Key InChIKey=KGLHLZYBYAUNGT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134392   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134392(CHEMBL3747423)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134392(CHEMBL3747423)
Affinity DataIC50:  38nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed