BDBM50135249 (S)-1-((2S,4R)-4-(5-fluorobenzo[b]thiophen-2-yl)-2-methylpiperidin-1-yl)-3-(2-methyl-1H-indol-4-yloxy)propan-2-ol::(S)-1-[(2S,4R)-4-(5-Fluoro-benzo[b]thiophen-2-yl)-2-methyl-piperidin-1-yl]-3-(2-methyl-1H-indol-4-yloxy)-propan-2-ol::CHEMBL129238

SMILES C[C@H]1C[C@@H](CCN1C[C@H](O)COc1cccc2[nH]c(C)cc12)c1cc2cc(F)ccc2s1

InChI Key InChIKey=WEGCLSBGECOYJJ-UEXGIBASSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50135249   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135249((S)-1-((2S,4R)-4-(5-fluorobenzo[b]thiophen-2-yl)-2...)
Affinity DataKi:  0.240nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135249((S)-1-((2S,4R)-4-(5-fluorobenzo[b]thiophen-2-yl)-2...)
Affinity DataKi:  0.240nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135249((S)-1-((2S,4R)-4-(5-fluorobenzo[b]thiophen-2-yl)-2...)
Affinity DataKi:  5.65nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135249((S)-1-((2S,4R)-4-(5-fluorobenzo[b]thiophen-2-yl)-2...)
Affinity DataKi:  5.70nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in human using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed