BDBM50135542 (S)-N-((R)-Benzyloxymethyl-cyano-methyl)-2-phenylamino-3-m-tolyl-propionamide::CHEMBL133508

SMILES Cc1cccc(C[C@H](Nc2ccccc2)C(=O)N[C@@H](COCc2ccccc2)C#N)c1

InChI Key InChIKey=SSNVUEXJJQDRMC-RPBOFIJWSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135542   

TargetCathepsin S(Homo sapiens (Human))
Novartis Institute Of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135542((S)-N-((R)-Benzyloxymethyl-cyano-methyl)-2-phenyla...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibtitory activity against cathepsin S (catS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Institute Of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135542((S)-N-((R)-Benzyloxymethyl-cyano-methyl)-2-phenyla...)
Affinity DataIC50:  194nMAssay Description:Inhibtitory activity against cathepsin B (catB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institute Of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135542((S)-N-((R)-Benzyloxymethyl-cyano-methyl)-2-phenyla...)
Affinity DataIC50:  220nMAssay Description:Inhibtitory activity against cathepsin L (catL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed