BDBM50136573 CHEMBL3752047
SMILES CN1CCN(CC1)C(=O)Nc1ccc(C[C@H](NC(=O)\C=C\c2cc(Cl)ccc2-n2cnnn2)C(=O)Nc2ccc(cc2)C(O)=O)cc1
InChI Key InChIKey=NWILZYMDURQVEC-PEOFMFGLSA-N
Data 12 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50136573
Affinity DataKi: 2nMAssay Description:Inhibition of human coagulation factor 11a assessed as substrate hydrolysis to p-nitroaniline incubated for 10 to 120 mins by spectrophotometry analy...More data for this Ligand-Target Pair
Affinity DataKi: 59nMAssay Description:Inhibition of human plasma kallikreinMore data for this Ligand-Target Pair
Affinity DataKi: >3.70E+3nMAssay Description:Inhibition of human coagulation factor 12aMore data for this Ligand-Target Pair
Affinity DataKi: >6.20E+3nMAssay Description:Inhibition of human trypsinMore data for this Ligand-Target Pair
Affinity DataKi: >8.60E+3nMAssay Description:Inhibition of human tissue plasminogen activatorMore data for this Ligand-Target Pair
Affinity DataKi: >9.00E+3nMAssay Description:Inhibition of human coagulation factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: >1.30E+4nMAssay Description:Inhibition of human coagulation factor 7aMore data for this Ligand-Target Pair
Affinity DataKi: >1.30E+4nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: >1.50E+4nMAssay Description:Inhibition of human urokinaseMore data for this Ligand-Target Pair
Affinity DataKi: >2.40E+4nMAssay Description:Inhibition of human coagulation factor 9aMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of human tissue kallikreinMore data for this Ligand-Target Pair
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of human activated protein CMore data for this Ligand-Target Pair