BDBM50137208 1-{4-[4-(1H-Indol-5-ylamino)-thieno[3,2-d]pyrimidin-6-yl]-benzyl}-isonicotinamide::CHEMBL311109

SMILES NC(=O)C1CCN(Cc2ccc(cc2)-c2cc3ncnc(Nc4ccc5[nH]ccc5c4)c3s2)CC1

InChI Key InChIKey=PSRIIUUKNWOHQJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50137208   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50137208(1-{4-[4-(1H-Indol-5-ylamino)-thieno[3,2-d]pyrimidi...)
Affinity DataIC50:  7nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50137208(1-{4-[4-(1H-Indol-5-ylamino)-thieno[3,2-d]pyrimidi...)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed