BDBM50137576 3-[1-{3-[3-(4-Hydroxy-piperidin-1-yl)-propyl]-4,5,6,7-tetrahydro-1H-indol-2-yl}-meth-(Z)-ylidene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid methylamide::CHEMBL55496

SMILES CNS(=O)(=O)c1ccc2NC(=O)\C(=C/c3[nH]c4CCCCc4c3CCCN3CCC(O)CC3)c2c1

InChI Key InChIKey=SKMKVAWCYDFONZ-JWGURIENSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50137576   

TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Sugen

Curated by ChEMBL
LigandPNGBDBM50137576(3-[1-{3-[3-(4-Hydroxy-piperidin-1-yl)-propyl]-4,5,...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against Fyn tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Sugen

Curated by ChEMBL
LigandPNGBDBM50137576(3-[1-{3-[3-(4-Hydroxy-piperidin-1-yl)-propyl]-4,5,...)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibitory activity against PDGFRbeta tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Sugen

Curated by ChEMBL
LigandPNGBDBM50137576(3-[1-{3-[3-(4-Hydroxy-piperidin-1-yl)-propyl]-4,5,...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Sugen

Curated by ChEMBL
LigandPNGBDBM50137576(3-[1-{3-[3-(4-Hydroxy-piperidin-1-yl)-propyl]-4,5,...)
Affinity DataIC50:  50nMAssay Description:Inhibitory activity against cellular Src protein tryrosine kinase using the actin ring assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Sugen

Curated by ChEMBL
LigandPNGBDBM50137576(3-[1-{3-[3-(4-Hydroxy-piperidin-1-yl)-propyl]-4,5,...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibitory activity against Fibroblast growth factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Sugen

Curated by ChEMBL
LigandPNGBDBM50137576(3-[1-{3-[3-(4-Hydroxy-piperidin-1-yl)-propyl]-4,5,...)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Sugen

Curated by ChEMBL
LigandPNGBDBM50137576(3-[1-{3-[3-(4-Hydroxy-piperidin-1-yl)-propyl]-4,5,...)
Affinity DataIC50:  900nMAssay Description:Inhibitory activity against cellular Src protein tryrosine kinase using the actin ring assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Sugen

Curated by ChEMBL
LigandPNGBDBM50137576(3-[1-{3-[3-(4-Hydroxy-piperidin-1-yl)-propyl]-4,5,...)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity against Yes tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed