BDBM50137582 CHEMBL292930::[4-(3-{2-[5-Methylsulfamoyl-2-oxo-1,2-dihydro-indol-(3Z)-ylidenemethyl]-4,5,6,7-tetrahydro-1H-indol-3-yl}-propyl)-piperazin-1-yl]-acetic acid

SMILES CNS(=O)(=O)c1ccc2NC(=O)\C(=C/c3[nH]c4CCCCc4c3CCCN3CCN(CC(O)=O)CC3)c2c1

InChI Key InChIKey=BPMIILWVKNVIKR-JWGURIENSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50137582   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Sugen

Curated by ChEMBL
LigandPNGBDBM50137582(CHEMBL292930 | [4-(3-{2-[5-Methylsulfamoyl-2-oxo-1...)
Affinity DataIC50:  400nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Sugen

Curated by ChEMBL
LigandPNGBDBM50137582(CHEMBL292930 | [4-(3-{2-[5-Methylsulfamoyl-2-oxo-1...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity against Src protein tryrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Sugen

Curated by ChEMBL
LigandPNGBDBM50137582(CHEMBL292930 | [4-(3-{2-[5-Methylsulfamoyl-2-oxo-1...)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity against Yes tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Sugen

Curated by ChEMBL
LigandPNGBDBM50137582(CHEMBL292930 | [4-(3-{2-[5-Methylsulfamoyl-2-oxo-1...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against cellular Src protein tryrosine kinase using the actin ring assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Sugen

Curated by ChEMBL
LigandPNGBDBM50137582(CHEMBL292930 | [4-(3-{2-[5-Methylsulfamoyl-2-oxo-1...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibitory activity against PDGFRbeta tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Sugen

Curated by ChEMBL
LigandPNGBDBM50137582(CHEMBL292930 | [4-(3-{2-[5-Methylsulfamoyl-2-oxo-1...)
Affinity DataIC50:  400nMAssay Description:Inhibitory activity against Fyn tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Sugen

Curated by ChEMBL
LigandPNGBDBM50137582(CHEMBL292930 | [4-(3-{2-[5-Methylsulfamoyl-2-oxo-1...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against Fibroblast growth factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Sugen

Curated by ChEMBL
LigandPNGBDBM50137582(CHEMBL292930 | [4-(3-{2-[5-Methylsulfamoyl-2-oxo-1...)
Affinity DataIC50:  100nMAssay Description:Inhibitory activity against Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed