BDBM50138735 (S)-4-isopropyl-3-methyl-2-(3-methylpiperidine-1-carbonyl)isoxazol-5(2H)-one::4-Isopropyl-3-methyl-2-((S)-3-methyl-piperidine-1-carbonyl)-2H-isoxazol-5-one::CHEMBL106126

SMILES CC(C)c1c(C)n(oc1=O)C(=O)N1CCC[C@H](C)C1

InChI Key InChIKey=XWESKOHENXWEAX-JTQLQIEISA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50138735   

TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50138735((S)-4-isopropyl-3-methyl-2-(3-methylpiperidine-1-c...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoprotein lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138735((S)-4-isopropyl-3-methyl-2-(3-methylpiperidine-1-c...)
Affinity DataIC50: >5.00E+4nMAssay Description:Compound was tested to inhibit lipoprotein lipase (LPL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138735((S)-4-isopropyl-3-methyl-2-(3-methylpiperidine-1-c...)
Affinity DataIC50: >5.00E+4nMAssay Description:Compound was tested to inhibit pancreatic lipase (PL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138735((S)-4-isopropyl-3-methyl-2-(3-methylpiperidine-1-c...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory concentration against butyrylcholinesterase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50138735((S)-4-isopropyl-3-methyl-2-(3-methylpiperidine-1-c...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138735((S)-4-isopropyl-3-methyl-2-(3-methylpiperidine-1-c...)
Affinity DataIC50: >5.00E+4nMAssay Description:Compound was tested to inhibit hepatic lipase (HL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138735((S)-4-isopropyl-3-methyl-2-(3-methylpiperidine-1-c...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibitory concentration against acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Rattus norvegicus (Rat))
University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50138735((S)-4-isopropyl-3-methyl-2-(3-methylpiperidine-1-c...)
Affinity DataIC50:  3nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50138735((S)-4-isopropyl-3-methyl-2-(3-methylpiperidine-1-c...)
Affinity DataIC50:  170nMAssay Description:Inhibition of hormone sensitive lipase (HSL).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed