BDBM50139140 CHEMBL3763404

SMILES Nc1nc2cc(ccc2c(=O)n1C[C@H]1CC[C@H](O1)c1ccccc1)-c1ccccc1

InChI Key InChIKey=ZFQQCJCOZGMLDR-OFNKIYASSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50139140   

TargetCathepsin D(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50139140(CHEMBL3763404)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of CatD (unknown origin) preincubated for 30 mins followed by DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS substrate addition by FRET assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
Latvian Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50139140(CHEMBL3763404)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 1 preincubated for 30 mins followed by DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS substrate addition...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Latvian Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50139140(CHEMBL3763404)
Affinity DataIC50:  340nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 preincubated for 30 mins followed by DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS substrate addition...More data for this Ligand-Target Pair