BDBM50139357 CHEMBL345803::Dimethyl-[2-(4-phenyl-thiazol-2-ylsulfanyl)-ethyl]-amine::N,N-dimethyl-2-(4-phenylthiazol-2-ylthio)ethanamine

SMILES CN(C)CCSc1nc(cs1)-c1ccccc1

InChI Key InChIKey=OFZLYUMNCUQVJM-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50139357   

Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50139357(CHEMBL345803 | Dimethyl-[2-(4-phenyl-thiazol-2-yls...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50139357(CHEMBL345803 | Dimethyl-[2-(4-phenyl-thiazol-2-yls...)
Affinity DataKi:  12nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in CHO ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139357(CHEMBL345803 | Dimethyl-[2-(4-phenyl-thiazol-2-yls...)
Affinity DataKi:  210nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 1A receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in HeL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139357(CHEMBL345803 | Dimethyl-[2-(4-phenyl-thiazol-2-yls...)
Affinity DataKi:  640nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 2A receptor by the displacement of [3H]-Ketanserin radioligand from the cloned receptor expressed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139357(CHEMBL345803 | Dimethyl-[2-(4-phenyl-thiazol-2-yls...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity towards human dopamine receptor D2 by the displacement of [3H]-Spiperone radioligand from the cloned receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed