BDBM50140074 CHEMBL2059155::US10227373, Compound 3-Bromo-3-deazaneplanocin

SMILES Nc1ncc(Br)c2n(cnc12)[C@@H]1C=C(CO)[C@@H](O)[C@H]1O

InChI Key InChIKey=PDMBCGAGDFHPGP-ONOSFVFSSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50140074   

TargetAdenosylhomocysteinase(Oryctolagus cuniculus (Rabbit))
Auburn University

US Patent
LigandPNGBDBM50140074(CHEMBL2059155 | US10227373, Compound 3-Bromo-3-dea...)
Affinity DataIC50:  2.70nMAssay Description:As a consequence of "D"-Isoneplanocin and "L"-Isoneplanocin, being isomers of Neplanocin A, which on one hand is a potent inhibitor of S-adenosylhomo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetS-adenosylhomocysteine hydrolase-like protein 1(Homo sapiens (Human))
Auburn University

Curated by ChEMBL
LigandPNGBDBM50140074(CHEMBL2059155 | US10227373, Compound 3-Bromo-3-dea...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of S-adenosylhomocysteine hydrolase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed