BDBM50140723 5-(4-methoxyphenyl)-3-phenyl-(3R,3aS,6aR)-spiro[perhydrofuro[3,4-c]pyrrole-1,2'-(2',3'-dihydro-1'H-indene)]-1',3',4,6-tetraone::CHEMBL28432

SMILES COc1ccc(cc1)-n1c(O)c2C(OC3(C(=O)c4ccccc4C3=O)c2c1O)c1ccccc1

InChI Key InChIKey=POARSKSBXGHKQY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50140723   

TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140723(5-(4-methoxyphenyl)-3-phenyl-(3R,3aS,6aR)-spiro[pe...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140723(5-(4-methoxyphenyl)-3-phenyl-(3R,3aS,6aR)-spiro[pe...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase, mitochondrial(Homo sapiens (Human))
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140723(5-(4-methoxyphenyl)-3-phenyl-(3R,3aS,6aR)-spiro[pe...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against human phenylalanyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed