BDBM50141085 6-[4-(2-Pyrrolidin-1-yl-ethoxy)-5,6,7,8-tetrahydro-naphthalen-1-yl]-pyridin-2-ylamine::CHEMBL42968

SMILES Nc1cccc(n1)-c1ccc(OCCN2CCCC2)c2CCCCc12

InChI Key InChIKey=ZMWHHNZCXGTSLB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50141085   

TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141085(6-[4-(2-Pyrrolidin-1-yl-ethoxy)-5,6,7,8-tetrahydro...)
Affinity DataIC50:  141nMAssay Description:In vitro inhibition of human neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141085(6-[4-(2-Pyrrolidin-1-yl-ethoxy)-5,6,7,8-tetrahydro...)
Affinity DataIC50:  2.22E+3nMAssay Description:In vitro inhibition of human endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141085(6-[4-(2-Pyrrolidin-1-yl-ethoxy)-5,6,7,8-tetrahydro...)
Affinity DataIC50:  80nMAssay Description:In vitro inhibition of rat neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141085(6-[4-(2-Pyrrolidin-1-yl-ethoxy)-5,6,7,8-tetrahydro...)
Affinity DataIC50:  358nMAssay Description:In vitro inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed