BDBM50141196 1-[3-methyl-2-[2-methyl-1-(2-pyrazinylcarboxamido)-(1R)-propylcarboxamido]-(2R)-butanoyl]-5-{1-[1-methyl-2-(1-naphthyl)-2-oxo-(1S)-ethylcarbamoylcarbonyl]butylcarbamoyl}-(3R,5S)-tetrahydro-1H-3-pyrrolyl 1,2,3,4-tetrahydro-2-isoquinolinec::CHEMBL284771

SMILES CCCC(NC(=O)[C@@H]1C[C@H](CN1C(=O)[C@H](NC(=O)[C@H](NC(=O)c1cnccn1)C(C)C)C(C)C)OC(=O)N1CCc2ccccc2C1)C(=O)C(=O)N[C@@H](C)C(=O)c1cccc2ccccc12

InChI Key InChIKey=SSKVGHVPLCLPQX-WOXODRQUSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50141196   

TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141196(1-[3-methyl-2-[2-methyl-1-(2-pyrazinylcarboxamido)...)
Affinity DataKi: <200nMAssay Description:Binding inhibition of hepatitis C virus NS3.4A protease 2 using p-nitroaniline assay (pNA); <0.2 (0.18)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141196(1-[3-methyl-2-[2-methyl-1-(2-pyrazinylcarboxamido)...)
Affinity DataIC50:  750nMAssay Description:Binding inhibition of hepatitis C virus NS3.4A protease 2 using a reverse phase HPLC based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed