BDBM50141457 (5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-[2-(3-hydroxy-3-methyl-butyl)-4-methoxy-phenyl]-2-isopropylamino-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL37920

SMILES COc1ccc([C@H]2[C@@H]([C@H](c3ccc(NC(C)C)nc23)c2ccc3OCOc3c2)C(O)=O)c(CCC(C)(C)O)c1

InChI Key InChIKey=YAWKZANKTNYRSZ-HZFUHODCSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50141457   

TargetEndothelin receptor type B(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141457((5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-[2-(3-hydroxy...)
Affinity DataIC50:  23nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141457((5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-[2-(3-hydroxy...)
Affinity DataIC50:  0.0650nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed