BDBM50144160 CHEMBL304019::N-[6-(4-Chloro-phenyl)-1-methoxy-6H-benzo[c]chromen-8-yl]-methanesulfonamide

SMILES COc1cccc2OC(c3ccc(Cl)cc3)c3cc(NS(C)(=O)=O)ccc3-c12

InChI Key InChIKey=KVKWTXCWMNRXJC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50144160   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144160(CHEMBL304019 | N-[6-(4-Chloro-phenyl)-1-methoxy-6H...)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]dexamethasone from human Glucocorticoid receptor (GR); Value ranges from 9-12 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144160(CHEMBL304019 | N-[6-(4-Chloro-phenyl)-1-methoxy-6H...)
Affinity DataIC50:  129nMAssay Description:Effect on human Glucocorticoid receptor (GR) in a whole cell assay to measure functional cellular GR-antagonism (GRAF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed