BDBM50144306 3-(3-Iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL66068

SMILES COC(=O)C1C2CCC(CC1c1cccc(I)c1)N2

InChI Key InChIKey=GPTFOAJWBIXTMY-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50144306   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Yale School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50144306(3-(3-Iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-car...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to serotonin transporter (SERT) in membranes of cells selectively expressing the human genes for SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50144306(3-(3-Iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-car...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to serotonin transporter (SERT) in rat forebrain tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50144306(3-(3-Iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-car...)
Affinity DataKi:  21nMAssay Description:Binding affinity to dopamine transporter (DAT) in rat forebrain tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Yale School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50144306(3-(3-Iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-car...)
Affinity DataKi:  118nMAssay Description:Binding affinity to norepinephrine (NE) transporter in membranes of cells selectively expressing the human genes for NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Yale School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50144306(3-(3-Iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-car...)
Affinity DataKi:  282nMAssay Description:Binding affinity to norepinephrine (NE) transporter in rat forebrain tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Yale School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50144306(3-(3-Iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-car...)
Affinity DataKi:  438nMAssay Description:Binding affinity to dopamine transporter in membranes of cells selectively expressing the human genes for DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed