BDBM50144463 CHEMBL71871::N-(3-Dibenzylamino-2-hydroxymethyl-phenyl)-methanesulfonamide

SMILES CS(=O)(=O)Nc1cccc(N(Cc2ccccc2)Cc2ccccc2)c1CO

InChI Key InChIKey=VIZJBWNADGOMCJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50144463   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144463(CHEMBL71871 | N-(3-Dibenzylamino-2-hydroxymethyl-p...)
Affinity DataIC50:  56nMAssay Description:Binding affinity against human Glucocorticoid receptor (GR) using [3H]-dexamethasone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144463(CHEMBL71871 | N-(3-Dibenzylamino-2-hydroxymethyl-p...)
Affinity DataIC50:  56nMAssay Description:Inhibition of [3H]-dexamethasone binding to glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144463(CHEMBL71871 | N-(3-Dibenzylamino-2-hydroxymethyl-p...)
Affinity DataIC50:  840nMAssay Description:Inhibition of glucocorticoid receptor dexamethasone responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed