BDBM50144807 7-Chloro-3-hydroxy-6-[1,2,4]triazol-4-yl-1H-quinazoline-2,4-dione::7-chloro-3-hydroxy-6-(4H-1,2,4-triazol-4-yl)quinazoline-2,4(1H,3H)-dione::CHEMBL310286

SMILES On1c(=O)[nH]c2cc(Cl)c(cc2c1=O)-n1cnnc1

InChI Key InChIKey=NROYJBQQKRDBOW-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50144807   

TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50144807(7-Chloro-3-hydroxy-6-[1,2,4]triazol-4-yl-1H-quinaz...)
Affinity DataKi:  6.60nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 preincubated for 15 mins prior to testing by phenol red based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50144807(7-Chloro-3-hydroxy-6-[1,2,4]triazol-4-yl-1H-quinaz...)
Affinity DataKi:  33nMAssay Description:Compound was tested for inhibition of bovine cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50144807(7-Chloro-3-hydroxy-6-[1,2,4]triazol-4-yl-1H-quinaz...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 preincubated for 15 mins prior to testing by phenol red based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50144807(7-Chloro-3-hydroxy-6-[1,2,4]triazol-4-yl-1H-quinaz...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins prior to testing by phenol red based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50144807(7-Chloro-3-hydroxy-6-[1,2,4]triazol-4-yl-1H-quinaz...)
Affinity DataKi: >1.00E+5nMAssay Description:Ability of compound to displace [3H]-glycine from N-methyl-D-aspartate glutamate receptor 1 from in cerebral cortex synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed