BDBM50145091 CHEMBL3763164

SMILES CC(C)c1ccc(cc1)C1C(Nc2cccc3c2c1n[nH]c3=O)c1ccc(CN(C)C)cc1

InChI Key InChIKey=PRXUVUNGLYWTRB-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50145091   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Biomarin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50145091(CHEMBL3763164)
Affinity DataEC50:  15nMAssay Description:Inhibition of PARP in human LoVo cells assessed as inhibition of poly(ADP)-ribose polymerization for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Biomarin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50145091(CHEMBL3763164)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of human PARP1 using [3H]NAD as substrate after 1 min by microplate scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed