BDBM50147298 4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxylic acid (3-fluoro-benzyl)-methyl-amide::CHEMBL107365::N-(3-fluorobenzyl)-4-isopropyl-N,3-dimethyl-5-oxoisoxazole-2(5H)-carboxamide

SMILES CC(C)c1c(C)n(oc1=O)C(=O)N(C)Cc1cccc(F)c1

InChI Key InChIKey=TZFMKGLPQMWSAN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50147298   

TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147298(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147298(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Affinity DataIC50:  12nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Rattus norvegicus (Rat))
University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50147298(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Affinity DataIC50:  5nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed