BDBM50148331 2-(4-Difluoromethoxy-phenyl)-5,5a,6,7,9,9a-hexahydro-2H-8-thia-1,2,5-triaza-cyclopenta[a]naphthalen-3-one::CHEMBL423690

SMILES FC(F)Oc1ccc(cc1)-n1[nH]c2C3CSCCC3N=Cc2c1=O

InChI Key InChIKey=MPEKCHDBHNYAJG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50148331   

TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148331(2-(4-Difluoromethoxy-phenyl)-5,5a,6,7,9,9a-hexahyd...)
Affinity DataKi:  0.380nMAssay Description:In vitro binding affinity against gamma-aminobutyric acid A receptor, alpha 1 expressed in L(tk) cells by displacement of [3H]-Ro-15-1788More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148331(2-(4-Difluoromethoxy-phenyl)-5,5a,6,7,9,9a-hexahyd...)
Affinity DataKi:  0.890nMAssay Description:In vitro displacement of [3H]-Ro-15-1788 from human GABA-A receptor alpha2-beta3-gamma2 subunits expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed