BDBM50149855 CHEMBL182916::{(2S,5R)-4-[2-(4-Methoxy-phenylsulfanyl)-phenyl]-2,5-dimethyl-piperazin-1-yl}-acetic acid

SMILES COc1ccc(Sc2ccccc2N2C[C@H](C)N(CC(O)=O)C[C@H]2C)cc1

InChI Key InChIKey=BDOUEVZZKRWFQZ-JKSUJKDBSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50149855   

TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50149855(CHEMBL182916 | {(2S,5R)-4-[2-(4-Methoxy-phenylsulf...)
Affinity DataIC50:  5.30E+4nMAssay Description:Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporterChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed