BDBM501505 3-methyl-1-[1-methylpropyl]-5-(2-propoxy-3- pyridyl)-N-(1H-pyrazol-3- ylmethyl)pyrazolo[4,3-b]pyridin-7-amine, enantiomer 2::US11026923, Example 135
SMILES CCCOc1ncccc1-c1cc(NCc2cc[nH]n2)c(NC(C)CC)c(n1)C(C)=N
InChI Key
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 501505
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(Homo sapiens (Human))
H. Lundbeck
US Patent
H. Lundbeck
US Patent
Affinity DataIC50: 1.90nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C(Homo sapiens (Human))
H. Lundbeck
US Patent
H. Lundbeck
US Patent
Affinity DataIC50: 3.60nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B(Homo sapiens (Human))
H. Lundbeck
US Patent
H. Lundbeck
US Patent
Affinity DataIC50: 0.0950nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...More data for this Ligand-Target Pair