BDBM50150702 3-Imidazo[1,2-a]pyridin-3-yl-4-[2-(piperidine-1-carbonyl)-1,2,3,4-tetrahydro-[1,4]diazepino[6,7,1-hi]indol-7-yl]-pyrrole-2,5-dione::CHEMBL362588
SMILES O=C(N1CCCCC1)N1CCn2cc(C3=C(C(=O)NC3=O)c3cnc4ccccn34)c3cccc(C1)c23
InChI Key InChIKey=HHSIUHRARDLCPM-UHFFFAOYSA-N
Data 13 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50150702
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human Cyclin-dependent kinase 2More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of Glycogen synthase kinase-3 beta dependent Tau protein serine-396 phosphorylation in human SY5Y cellsMore data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human PDK-1More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human Glycogen synthase kinase-3 betaMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 20(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human MLK7More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit beta(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human Protein kinase A betaMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human Akt1More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human TGF-beta type II receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human Cyclin-dependent kinase 4More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibitory concentration to inhibit Ser396 phosphorylation of tau, a natural substrate of GSK-3 in SY5Y cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Inhibition of human Protein kinase C beta 2More data for this Ligand-Target Pair