BDBM50151536 4-[5-(4-Chloro-phenyl)-3-methyl-3H-[1,3,4]thiadiazol-(2Z)-ylideneamino]-benzoic acid::CHEMBL183156

SMILES Cn1nc(s\c1=N/c1ccc(cc1)C(O)=O)-c1ccc(Cl)cc1

InChI Key InChIKey=CDWRTACTPFUHEY-VLGSPTGOSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50151536   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151536(4-[5-(4-Chloro-phenyl)-3-methyl-3H-[1,3,4]thiadiaz...)
Affinity DataIC50:  4.04E+4nMAssay Description:Inhibition of human Phosphodiesterase 5 purified from MCF-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50151536(4-[5-(4-Chloro-phenyl)-3-methyl-3H-[1,3,4]thiadiaz...)
Affinity DataIC50:  2.89E+4nMAssay Description:Inhibition of human Phosphodiesterase 1 purified from THP-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151536(4-[5-(4-Chloro-phenyl)-3-methyl-3H-[1,3,4]thiadiaz...)
Affinity DataIC50: >1.01E+5nMAssay Description:Inhibition of human Phosphodiesterase 4D3 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151536(4-[5-(4-Chloro-phenyl)-3-methyl-3H-[1,3,4]thiadiaz...)
Affinity DataIC50:  3.07E+4nMAssay Description:Inhibition of human Phosphodiesterase 3A3 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151536(4-[5-(4-Chloro-phenyl)-3-methyl-3H-[1,3,4]thiadiaz...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of human Phosphodiesterase 7A1 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed