BDBM50151776 3-(2,4-Difluoro-phenylsulfanyl)-6-methanesulfonyl-1H-indole-2-carboxylic acid methyl ester::CHEMBL183101

SMILES COC(=O)c1[nH]c2cc(ccc2c1Sc1ccc(F)cc1F)S(C)(=O)=O

InChI Key InChIKey=YMNRYTSZOBEQFB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50151776   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50151776(3-(2,4-Difluoro-phenylsulfanyl)-6-methanesulfonyl-...)
Affinity DataIC50:  380nMAssay Description:Inhibitory concentration against human whole blood Prostaglandin G/H synthase 2 enzyme activity was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50151776(3-(2,4-Difluoro-phenylsulfanyl)-6-methanesulfonyl-...)
Affinity DataIC50:  380nMAssay Description:In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50151776(3-(2,4-Difluoro-phenylsulfanyl)-6-methanesulfonyl-...)
Affinity DataIC50:  1.72E+4nMAssay Description:Inhibitory concentration against human whole blood Prostaglandin G/H synthase 1 enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed