BDBM50153381 CHEMBL186482::Trifluoro-acetate1-(2-fluoro-benzyl)-3-[(R)-4-(4-methoxycarbonylmethyl-benzylcarbamoyl)-thiazolidin-3-yl]-3-oxo-propyl-ammonium;

SMILES COC(=O)Cc1ccc(CNC(=O)[C@@H]2CSCN2C(=O)CC([NH3+])Cc2ccccc2F)cc1

InChI Key InChIKey=FZCVYOKVSXZELZ-QWAKEFERSA-O

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50153381   

TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50153381(CHEMBL186482 | Trifluoro-acetate1-(2-fluoro-benzyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Fibroblast activation protein alpha (seprase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50153381(CHEMBL186482 | Trifluoro-acetate1-(2-fluoro-benzyl...)
Affinity DataIC50:  9.70E+3nMAssay Description:Inhibition of human Potassium channel HERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50153381(CHEMBL186482 | Trifluoro-acetate1-(2-fluoro-benzyl...)
Affinity DataIC50:  5.90E+4nMAssay Description:Inhibition of Quiescent cell prolyl dipeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50153381(CHEMBL186482 | Trifluoro-acetate1-(2-fluoro-benzyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Dipeptidylpeptidase IXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50153381(CHEMBL186482 | Trifluoro-acetate1-(2-fluoro-benzyl...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of prolyl endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXaa-Pro dipeptidase(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50153381(CHEMBL186482 | Trifluoro-acetate1-(2-fluoro-benzyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of prolidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50153381(CHEMBL186482 | Trifluoro-acetate1-(2-fluoro-benzyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Dipeptidylpeptidase VIIIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50153381(CHEMBL186482 | Trifluoro-acetate1-(2-fluoro-benzyl...)
Affinity DataIC50:  87nMAssay Description:Inhibition of human recombinant Dipeptidylpeptidase IVMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed