BDBM50153386 CHEMBL435882::Trifluoro-acetate1-(2-fluoro-benzyl)-3-oxo-3-[(S)-2-(4-trifluoromethyl-benzylcarbamoyl)-pyrrolidin-1-yl]-propyl-ammonium;

SMILES [NH3+]C(CC(=O)N1CCC[C@H]1C(=O)NCc1ccc(cc1)C(F)(F)F)Cc1ccccc1F

InChI Key InChIKey=BCERHNLMUQCEJQ-IJHRGXPZSA-O

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50153386   

TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50153386(CHEMBL435882 | Trifluoro-acetate1-(2-fluoro-benzyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Fibroblast activation protein alpha (seprase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50153386(CHEMBL435882 | Trifluoro-acetate1-(2-fluoro-benzyl...)
Affinity DataIC50:  721nMAssay Description:Inhibition of human recombinant Dipeptidylpeptidase IVMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXaa-Pro dipeptidase(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50153386(CHEMBL435882 | Trifluoro-acetate1-(2-fluoro-benzyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of prolidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50153386(CHEMBL435882 | Trifluoro-acetate1-(2-fluoro-benzyl...)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibition of Quiescent cell prolyl dipeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50153386(CHEMBL435882 | Trifluoro-acetate1-(2-fluoro-benzyl...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of Dipeptidylpeptidase VIIIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50153386(CHEMBL435882 | Trifluoro-acetate1-(2-fluoro-benzyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Dipeptidylpeptidase IXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50153386(CHEMBL435882 | Trifluoro-acetate1-(2-fluoro-benzyl...)
Affinity DataIC50:  870nMAssay Description:Inhibition of human Potassium channel HERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed