BDBM50155364 7-Chloro-2-oxo-4-[2-(tetrahydro-furan-2-yl)-ethoxy]-3-(3,4,5-trimethyl-phenyl)-1,2-dihydro-quinoline-6-carboxylic acid pyrimidin-4-ylamide::CHEMBL184819
SMILES Cc1cc(cc(C)c1C)-c1c(OCCC2CCCO2)c2cc(C(=O)Nc3ccncn3)c(Cl)cc2[nH]c1=O
InChI Key InChIKey=YWHAKGCRCVPYKM-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50155364
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Binding affinity towards human gonadotropin releasing hormone receptor expressed in CHO cells was determined by using [125I]-buserelin as radioligandMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Inhibition of GnRH-stimulated phosphatidyl inositol hydrolysis in CHO cells expressing GnRH receptorMore data for this Ligand-Target Pair