BDBM50155557 1-(4-Diethylamino-phenyl)-3-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-urea::CHEMBL185901
SMILES CCN(CC)c1ccc(NC(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)cc1
InChI Key InChIKey=GVTIVFCBPRVRQC-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50155557
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: >3.40E+3nMAssay Description:Inhibitory concentration required to inhibit Abl tyrosine kinaseMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
The First People'S Hospital Of Hangzhou
Curated by ChEMBL
The First People'S Hospital Of Hangzhou
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BCR-ABL kinase (unknown origin)More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration required to inhibit Bcr-Abl tyrosine kinaseMore data for this Ligand-Target Pair