BDBM50155575 1-[4-Methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-3-(2-pyrrolidin-1-yl-ethyl)-urea::CHEMBL363926

SMILES Cc1ccc(NC(=O)NCCN2CCCC2)cc1Nc1nccc(n1)-c1cccnc1

InChI Key InChIKey=NUZXYWIRCCEMEG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50155575   

TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
The First People'S Hospital Of Hangzhou

Curated by ChEMBL
LigandPNGBDBM50155575(1-[4-Methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...)
Affinity DataIC50:  8.91E+3nMAssay Description:Inhibition of BCR-ABL kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50155575(1-[4-Methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...)
Affinity DataIC50: >9.00E+3nMAssay Description:Inhibitory concentration required to inhibit Bcr-Abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed